LDN-27219 protein kinase targeting Things To Know Before You Buy
A person significantly attention-grabbing compound is LDN-27219. When most tTG inhibitors are built to bind into the protein crosslinking Energetic website, LDN-27219 instead binds into the nucleotide binding pocket on the enzyme whilst it is in its closed-point out conformation, and stabilizes that conformation to stop crosslinking activity.sevent